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Paul R McGuirk Selected Research

AER-271

1/2019The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest.
1/2019Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury.

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Paul R McGuirk Research Topics

Disease

2Brain Edema (Cerebral Edema)
01/2019 - 01/2019
1Ischemic Stroke
01/2019
1Neuroinflammatory Diseases
01/2019
1Heart Arrest (Cardiac Arrest)
01/2019
1Neurologic Manifestations (Neurological Manifestations)
01/2019
1Water Intoxication
01/2019
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2019
1Inflammation (Inflammations)
01/2018
1Reperfusion Injury
01/2018

Drug/Important Bio-Agent (IBA)

2AER-271IBA
01/2019 - 01/2019
1diazonaphthalenedisulfonic acid (NDS)IBA
01/2019
1Phosphates (Orthophosphate)IBA
01/2019
1salicylhydroxamic acid (SHAM)IBA
01/2019
1ProdrugsIBA
01/2019
1Aquaporins (Water Channels)IBA
01/2018

Therapy/Procedure

1Resuscitation
01/2019
1Therapeutics
01/2019
1Transplantation
01/2018